La somministrazione una volta al giorno non è stata valutata nei pazienti con insufficienza epatica. Se viene prescritto Cialis, deve essere eseguita un’attenta valutazione caso per caso del rapporto beneficio-rischio da parte del medico che lo prescrive.
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[34] Scientific tests on the consequences of sildenafil when used recreationally are limited, but recommend it has very little influence when employed by people that do not have erectile dysfunction. In one examine, a twenty five mg dose was proven to cause no important modify in erectile top quality, but did reduce the postejaculatory refractory time.[35] This examine also noted a substantial placebo outcome within the control group.[35]